Reaction Details Report a problem with these data
Target
Bifunctional epoxide hydrolase 2
Ligand
BDBM41896
Substrate
n/a
Meas. Tech.
sEH_DR_Inh_Infinite200_Fluorescence_01072008
IC50
54±n/a nM
Citation
 PubChem, PC sEH_DR_Inh_Infinite200_Fluorescence_01072008 PubChem Bioassay (2008)[AID] 
Target
Name:
Bifunctional epoxide hydrolase 2
Synonyms:
Cytosolic epoxide hydrolase 2 | EBifunctional epoxide hydrolase 2 | EPHX2 | Epoxide hydratase | HYES_HUMAN | Lipid-phosphate phosphatase | Soluble epoxide hydrolase (sEH) | epoxide hydrolase 2, cytoplasmic
Type:
Enzyme
Mol. Mass.:
62613.07
Organism:
Homo sapiens (Human)
Description:
P34913
Residue:
555
Sequence:
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM
  
Inhibitor
Name:
BDBM41896
Synonyms:
1-Pyrimidin-2-yl-piperidine-3-carboxylic acid (4-phenoxy-phenyl)-amide | MLS000032893 | N-(4-phenoxyphenyl)-1-(2-pyrimidinyl)-3-piperidinecarboxamide | N-(4-phenoxyphenyl)-1-(2-pyrimidyl)nipecotamide | N-(4-phenoxyphenyl)-1-pyrimidin-2-yl-piperidine-3-carboxamide | N-(4-phenoxyphenyl)-1-pyrimidin-2-ylpiperidine-3-carboxamide | SMR000007018 | cid_647007
Type:
Small organic molecule
Emp. Form.:
C22H22N4O2
Mol. Mass.:
374.4357
SMILES:
O=C(Nc1ccc(Oc2ccccc2)cc1)C1CCCN(C1)c1ncccn1
Structure:
Search PDB for entries with ligand similarity: