Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM39118
Substrate
n/a
Meas. Tech.
In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study
IC50
6780±1900 nM
Citation
 PubChem, PC In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM39118
Synonyms:
2-mesyl-4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidine | 4-(3-methoxyphenyl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine | MLS-0066988.0001 | US11725000, Compound 52 | cid_751044
Type:
Small organic molecule
Emp. Form.:
C13H11F3N2O3S
Mol. Mass.:
332.298
SMILES:
COc1cccc(c1)-c1cc(nc(n1)S(C)(=O)=O)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: