Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM39185
Substrate
n/a
Meas. Tech.
In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study
IC50
1700±350 nM
Citation
 PubChem, PC In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM39185
Synonyms:
3-chloranyl-1-(4-methylphenyl)-4-[(4-methylphenyl)amino]pyrrole-2,5-dione | 3-chloro-4-(4-methylanilino)-1-(4-methylphenyl)pyrrole-2,5-dione | 3-chloro-4-(p-toluidino)-1-(p-tolyl)-3-pyrroline-2,5-quinone | MLS-0111861.0001 | cid_728014
Type:
Small organic molecule
Emp. Form.:
C18H15ClN2O2
Mol. Mass.:
326.777
SMILES:
Cc1ccc(cc1)N=C1C(Cl)C(=O)N(C1=O)c1ccc(C)cc1 |w:7.7|
Structure:
Search PDB for entries with ligand similarity: