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Target
Galanin receptor type 2
Ligand
BDBM36845
Substrate
n/a
Meas. Tech.
Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2)
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2) PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM36845
Synonyms:
5-tert-Butyl-2-methyl-2H-pyrazole-3-carboxylic acid 4-(2-oxo-pyrrolidin-1-yl)-benzylamide | 5-tert-butyl-2-methyl-N-[[4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]methyl]pyrazole-3-carboxamide | 5-tert-butyl-2-methyl-N-[[4-(2-oxo-1-pyrrolidinyl)phenyl]methyl]-3-pyrazolecarboxamide | 5-tert-butyl-2-methyl-N-[[4-(2-oxopyrrolidin-1-yl)phenyl]methyl]pyrazole-3-carboxamide | 5-tert-butyl-N-[4-(2-ketopyrrolidino)benzyl]-2-methyl-pyrazole-3-carboxamide | MLS000074502 | SMR000007305 | cid_648690
Type:
Small organic molecule
Emp. Form.:
C20H26N4O2
Mol. Mass.:
354.446
SMILES:
Cn1nc(cc1C(=O)NCc1ccc(cc1)N1CCCC1=O)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: