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Target
Galanin receptor type 2
Ligand
BDBM36855
Substrate
n/a
Meas. Tech.
Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2)
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2) PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM36855
Synonyms:
(5,6-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-[2-(4-methoxy-phenyl)-ethyl]-amine | (5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-[2-(4-methoxyphenyl)ethyl]amine | MLS000076630 | N-[2-(4-methoxyphenyl)ethyl]-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | SMR000007703 | cid_650985
Type:
Small organic molecule
Emp. Form.:
C16H19N5O
Mol. Mass.:
297.355
SMILES:
COc1ccc(CCNc2c(C)c(C)nc3ncnn23)cc1
Structure:
Search PDB for entries with ligand similarity: