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Target
Galanin receptor type 2
Ligand
BDBM42059
Substrate
n/a
Meas. Tech.
Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2)
IC50
45250±n/a nM
Citation
 PubChem, PC Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2) PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM42059
Synonyms:
MLS000391275 | N-[(Z)-(3-amino-1-isoindolylidene)amino]-4-(4-fluorophenyl)-2-thiazolamine | N-[(Z)-(3-aminoisoindol-1-ylidene)amino]-4-(4-fluorophenyl)-1,3-thiazol-2-amine | N-[(Z)-(3-azanylisoindol-1-ylidene)amino]-4-(4-fluorophenyl)-1,3-thiazol-2-amine | SMR000260312 | [(Z)-(3-aminoisoindol-1-ylidene)amino]-[4-(4-fluorophenyl)thiazol-2-yl]amine | cid_6261459
Type:
Small organic molecule
Emp. Form.:
C17H12FN5S
Mol. Mass.:
337.374
SMILES:
NC1=NC(=NNc2nc(cs2)-c2ccc(F)cc2)c2ccccc12 |w:4.4,t:1|
Structure:
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