Reaction Details Report a problem with these data
Target
Glyceraldehyde-3-phosphate dehydrogenase
Ligand
BDBM31737
Substrate
n/a
Meas. Tech.
GAPDH Dose Response Colorimetric Assay
IC50
87100±7580 nM
Citation
 PubChem, PC GAPDH Dose Response Colorimetric Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Glyceraldehyde-3-phosphate dehydrogenase
Synonyms:
G3P_HUMAN | GAPD | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase liver
Type:
PROTEIN
Mol. Mass.:
36060.86
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511315
Residue:
335
Sequence:
MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE
  
Inhibitor
Name:
BDBM31737
Synonyms:
2-[5-[(Z)-(1-keto-5,7-dimethyl-thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]-2-furyl]benzoic acid | 2-[5-[(Z)-(5,7-dimethyl-1-oxidanylidene-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid | 2-[5-[(Z)-(5,7-dimethyl-1-oxo-2-thiazolo[3,2-a]benzimidazolylidene)methyl]-2-furanyl]benzoic acid | 2-[5-[(Z)-(5,7-dimethyl-1-oxo-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid | MLS-0091943.0001 | cid_5341943
Type:
Small organic molecule
Emp. Form.:
C23H16N2O4S
Mol. Mass.:
416.449
SMILES:
Cc1cc(C)c2nc3s\c(=C/c4ccc(o4)-c4ccccc4C(O)=O)c(=O)n3c2c1
Structure:
Search PDB for entries with ligand similarity: