Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM38870
Substrate
n/a
Meas. Tech.
Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM38870
Synonyms:
(7S,12R,15S)-12,15-dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one | (7S,12R,15S)-7-methyl-12,15-bis(oxidanyl)-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one | BREFELDIN A | MLS000069707 | SMR000058539 | cid_657314
Type:
Small organic molecule
Emp. Form.:
C16H24O4
Mol. Mass.:
280.3594
SMILES:
C[C@H]1CCCC=CC2C[C@H](O)CC2[C@H](O)C=CC(=O)O1
Structure:
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