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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42147
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42147
Synonyms:
4-[2-[4-(2-furoyl)piperazino]acetyl]-9-hydroxy-2,3-dihydro-1H-chromeno[3,4-b]pyridin-5-one | 4-[2-[4-(furan-2-carbonyl)piperazin-1-yl]acetyl]-9-hydroxy-2,3-dihydro-1H-chromeno[3,4-b]pyridin-5-one | 4-[2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]ethanoyl]-9-oxidanyl-2,3-dihydro-1H-chromeno[3,4-b]pyridin-5-one | 4-[2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-1-oxoethyl]-9-hydroxy-2,3-dihydro-1H-[1]benzopyrano[3,4-b]pyridin-5-one | 4-{[4-(2-furoyl)piperazin-1-yl]acetyl}-9-hydroxy-1,2,3,4-tetrahydro-5H-chromeno[3,4-b]pyridin-5-one | MLS000043269 | SMR000019889 | cid_3237512
Type:
Small organic molecule
Emp. Form.:
C23H23N3O6
Mol. Mass.:
437.4452
SMILES:
Oc1ccc2oc(=O)c3N(CCCc3c2c1)C(=O)CN1CCN(CC1)C(=O)c1ccco1
Structure:
Search PDB for entries with ligand similarity: