Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM42560
Substrate
n/a
Meas. Tech.
Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism
IC50
26730±n/a nM
Citation
 PubChem, PC Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42560
Synonyms:
MLS000700566 | N'-[3-nitro-4-(4-morpholinyl)benzylidene]pentanohydrazide | N-[(4-morpholin-4-yl-3-nitro-phenyl)methylideneamino]pentanamide | N-[(4-morpholin-4-yl-3-nitrophenyl)methylideneamino]pentanamide | N-[(4-morpholino-3-nitro-benzylidene)amino]valeramide | N-[[4-(4-morpholinyl)-3-nitrophenyl]methylideneamino]pentanamide | SMR000225666 | cid_4171370
Type:
Small organic molecule
Emp. Form.:
C16H22N4O4
Mol. Mass.:
334.3703
SMILES:
CCCCC(=O)N\N=C\c1ccc(N2CCOCC2)c(c1)[N+]([O-])=O
Structure:
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