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TargetApoptosis regulator Bcl-2
LigandBDBM33048
Substrate/Competitorn/a
Meas. Tech.Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2
EC50 760±n/a nM
Citation PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2 PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Apoptosis regulator Bcl-2
Name:Apoptosis regulator Bcl-2
Synonyms:Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | Bcl-2 Protein
Type:Homodimer or heterodimer
Mol. Mass.:26269.11
Organism:Homo sapiens (Human)
Description:P10415
Residue:239
Sequence:
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
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BDBM33048
NameBDBM33048
Synonyms:(5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydroxypropyl)-4-methyl-2,6-dioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile | 5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-2,6-diketo-4-methyl-nicotinonitrile | 5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-4-methyl-2,6-dioxo-3-pyridinecarbonitrile | 5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-4-methyl-2,6-dioxopyridine-3-carbonitrile | 5-[4-(dimethylamino)phenyl]imino-4-methyl-2,6-bis(oxidanylidene)-1-(3-oxidanylpropyl)pyridine-3-carbonitrile | MLS000089998 | SMR000024616 | cid_3239318
TypeSmall organic molecule
Emp. Form.C18H20N4O3
Mol. Mass.340.3764
SMILESCN(C)c1ccc(cc1)\N=C1/C(C)=C(C#N)C(=O)N(CCCO)C1=O |t:13|
Structure
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