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Target
Cyclin-dependent kinase 7
Ligand
BDBM32348
Substrate
n/a
Meas. Tech.
CDK7 counterscreen of confirmed PKD inhibitors-57K library addition
IC50
8222.176091±n/a nM
Citation
 PubChem, PC CDK7 counterscreen of confirmed PKD inhibitors-57K library addition PubChem Bioassay (2008)[AID] 
Target
Name:
Cyclin-dependent kinase 7
Synonyms:
39 kDa protein kinase | CAK | CAK1 | CDK-activating kinase | CDK-activating kinase 1 (CAK) | CDK7 | CDK7_HUMAN | CDKN7 | Cell division protein kinase 7 | Cyclin-Dependent Kinase 7 (CDK7) | Cyclin-dependent kinase 7 (CDK7/cyclin H) | MO15 | P39 Mo15 | STK1 | TFIIH basal transcription factor complex kinase subunit
Type:
Enzyme Subunit
Mol. Mass.:
39047.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
346
Sequence:
MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
  
Inhibitor
Name:
BDBM32348
Synonyms:
6-(2-methyl-2,3-dihydro-1H-indol-1-yl)-5-nitro-4-pyrimidinamine | 6-(2-methyl-2,3-dihydroindol-1-yl)-5-nitro-4-pyrimidinamine | 6-(2-methyl-2,3-dihydroindol-1-yl)-5-nitro-pyrimidin-4-amine | 6-(2-methyl-2,3-dihydroindol-1-yl)-5-nitropyrimidin-4-amine | MLS000665974 | SMR000294670 | [6-(2-methylindolin-1-yl)-5-nitro-pyrimidin-4-yl]amine | cid_2958734
Type:
Small organic molecule
Emp. Form.:
C13H13N5O2
Mol. Mass.:
271.2746
SMILES:
CC1Cc2ccccc2N1c1ncnc(N)c1[N+]([O-])=O
Structure:
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