Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43553
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
5664±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43553
Synonyms:
3-(2-furanylmethyl)-4-quinazolinone | 3-(2-furfuryl)quinazolin-4-one | 3-(furan-2-ylmethyl)quinazolin-4-one | MLS000080230 | SMR000036493 | cid_332456
Type:
Small organic molecule
Emp. Form.:
C13H10N2O2
Mol. Mass.:
226.2307
SMILES:
O=c1n(Cc2ccco2)cnc2ccccc12
Structure:
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