Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43555
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
2109±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43555
Synonyms:
2-(4-methyl-2-quinazolinyl)-1-phenylguanidine | 2-(4-methylquinazolin-2-yl)-1-phenyl-guanidine | 2-(4-methylquinazolin-2-yl)-1-phenylguanidine | MLS000037979 | SMR000040214 | cid_659193
Type:
Small organic molecule
Emp. Form.:
C16H15N5
Mol. Mass.:
277.3238
SMILES:
Cc1nc(NC(N)=Nc2ccccc2)nc2ccccc12 |w:7.7|
Structure:
Search PDB for entries with ligand similarity: