Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43562
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>6190±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43562
Synonyms:
2-(1-phenyltetrazol-5-yl)sulfanyl-5-propylsulfanyl-1,3,4-thiadiazole | 2-[(1-phenyl-1,2,3,4-tetrazol-5-yl)sulfanyl]-5-propylsulfanyl-1,3,4-thiadiazole | 2-[(1-phenyl-5-tetrazolyl)thio]-5-(propylthio)-1,3,4-thiadiazole | 2-[(1-phenyltetrazol-5-yl)thio]-5-(propylthio)-1,3,4-thiadiazole | MLS000056566 | SMR000064678 | cid_2536033
Type:
Small organic molecule
Emp. Form.:
C12H12N6S3
Mol. Mass.:
336.459
SMILES:
CCCSc1nnc(Sc2nnnn2-c2ccccc2)s1
Structure:
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