Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM40067
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
8061±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM40067
Synonyms:
MLS000062293 | N-(2-pyridinyl)-2-thiophen-2-ylacetamide | N-(2-pyridyl)-2-(2-thienyl)acetamide | N-2-pyridinyl-2-(2-thienyl)acetamide | N-pyridin-2-yl-2-thiophen-2-yl-ethanamide | N-pyridin-2-yl-2-thiophen-2-ylacetamide | SMR000071109 | cid_836204
Type:
Small organic molecule
Emp. Form.:
C11H10N2OS
Mol. Mass.:
218.275
SMILES:
O=C(Cc1cccs1)Nc1ccccn1
Structure:
Search PDB for entries with ligand similarity: