Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43594
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
8129±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43594
Synonyms:
2,3-dihydroindol-1-yl(3-pyridinyl)methanone | 2,3-dihydroindol-1-yl(pyridin-3-yl)methanone | MLS000106324 | SMR000103293 | cid_669080 | indolin-1-yl(3-pyridyl)methanone
Type:
Small organic molecule
Emp. Form.:
C14H12N2O
Mol. Mass.:
224.2579
SMILES:
O=C(N1CCc2ccccc12)c1cccnc1
Structure:
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