Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43611
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>619±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43611
Synonyms:
3-methyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-benzo[g]benzofurancarboxamide | 3-methyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzo[g][1]benzofuran-2-carboxamide | 3-methyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzo[g]benzofuran-2-carboxamide | MLS000569696 | SMR000155073 | cid_2128498
Type:
Small organic molecule
Emp. Form.:
C17H13N3O2S
Mol. Mass.:
323.369
SMILES:
Cc1nnc(NC(=O)c2oc3c(ccc4ccccc34)c2C)s1
Structure:
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