Reaction Details Report a problem with these data
Target
Wee1-like protein kinase
Ligand
BDBM43778
Substrate
n/a
Meas. Tech.
Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation PubChem Bioassay (2008)[AID] 
Target
Name:
Wee1-like protein kinase
Synonyms:
Serine/threonine-protein kinase WEE1 | WEE1 | WEE1 homolog (S. pombe) | WEE1_HUMAN
Type:
PROTEIN
Mol. Mass.:
71599.12
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1445054
Residue:
646
Sequence:
MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
  
Inhibitor
Name:
BDBM43778
Synonyms:
2-[4-(3,4-dimethylthieno[2,3-b]thiophen-5-yl)pyrimidin-2-yl]sulfanyl-N-(phenylmethyl)ethanamide | 2-[[4-(3,4-dimethyl-5-thieno[2,3-b]thiophenyl)-2-pyrimidinyl]thio]-N-(phenylmethyl)acetamide | MLS000860689 | N-benzyl-2-[4-(3,4-dimethylthieno[2,3-b]thiophen-5-yl)pyrimidin-2-yl]sulfanylacetamide | N-benzyl-2-[[4-(3,4-dimethylthieno[2,3-b]thiophen-5-yl)pyrimidin-2-yl]thio]acetamide | N1-benzyl-2-{[4-(3,4-dimethylthieno[2,3-b]thiophen-2-yl)pyrimidin-2-yl]thio}acetamide | SMR000459473 | cid_2820576
Type:
Small organic molecule
Emp. Form.:
C21H19N3OS3
Mol. Mass.:
425.59
SMILES:
Cc1csc2sc(c(C)c12)-c1ccnc(SCC(=O)NCc2ccccc2)n1
Structure:
Search PDB for entries with ligand similarity: