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Target
G2/mitotic-specific cyclin-B1
Ligand
BDBM43769
Substrate
n/a
Meas. Tech.
Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Counterscreen assay for inhibitors of Wee1 degradation: dose response cell-based assay to identify inhibitors of cyclin B degradation PubChem Bioassay (2008)[AID] 
Target
Name:
G2/mitotic-specific cyclin-B1
Synonyms:
CCNB | CCNB1 | CCNB1_HUMAN
Type:
Enzyme Subunit
Mol. Mass.:
48340.95
Organism:
Homo sapiens (Human)
Description:
P14635
Residue:
433
Sequence:
MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV
  
Inhibitor
Name:
BDBM43769
Synonyms:
3-[[4-(2-methyl-3-imidazo[1,2-a]pyridinyl)-2-thiazolyl]amino]phenol | 3-[[4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino]phenol | 3-[[4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-yl]amino]phenol | MLS000715629 | SMR000275608 | cid_3128426
Type:
Small organic molecule
Emp. Form.:
C17H14N4OS
Mol. Mass.:
322.384
SMILES:
Cc1nc2ccccn2c1-c1csc(Nc2cccc(O)c2)n1
Structure:
Search PDB for entries with ligand similarity: