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Target
E3 ubiquitin-protein ligase XIAP
Ligand
BDBM43782
Substrate
n/a
Meas. Tech.
Chemical Antagonists of IAP-family anti-apoptotic proteins confirmation
IC50
>200000±0 nM
Citation
 PubChem, PC Chemical Antagonists of IAP-family anti-apoptotic proteins confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
E3 ubiquitin-protein ligase XIAP
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN
Type:
Protein
Mol. Mass.:
56685.27
Organism:
Homo sapiens (Human)
Description:
P98170
Residue:
497
Sequence:
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS
  
Inhibitor
Name:
BDBM43782
Synonyms:
2-(1-ketoisoindolin-2-yl)propionic acid | 2-(3-oxidanylidene-1H-isoindol-2-yl)propanoic acid | 2-(3-oxo-1H-isoindol-2-yl)propanoic acid | MLS-0315756.0001 | cid_2764373
Type:
Small organic molecule
Emp. Form.:
C11H11NO3
Mol. Mass.:
205.2099
SMILES:
CC(N1Cc2ccccc2C1=O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: