Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44539
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44539
Synonyms:
6-[(Cyclohexyl-methyl-amino)-methyl]-N-(4-methoxy-phenyl)-[1,3,5]triazine-2,4-diamine | 6-[[cyclohexyl(methyl)amino]methyl]-2-N-(4-methoxyphenyl)-1,3,5-triazine-2,4-diamine | 6-[[cyclohexyl(methyl)amino]methyl]-N2-(4-methoxyphenyl)-1,3,5-triazine-2,4-diamine | MLS000067859 | SMR000122505 | [4-amino-6-(p-anisidino)-s-triazin-2-yl]methyl-cyclohexyl-methyl-amine | cid_750910
Type:
Small organic molecule
Emp. Form.:
C18H26N6O
Mol. Mass.:
342.4386
SMILES:
COc1ccc(Nc2nc(N)nc(CN(C)C3CCCCC3)n2)cc1
Structure:
Search PDB for entries with ligand similarity: