Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44541
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44541
Synonyms:
5-(4-Isobutoxy-benzyl)-pyrimidine-2,4-diamine | 5-[[4-(2-methylpropoxy)phenyl]methyl]pyrimidine-2,4-diamine | MLS000552195 | SMR000145909 | [2-amino-5-(4-isobutoxybenzyl)pyrimidin-4-yl]amine | cid_739795
Type:
Small organic molecule
Emp. Form.:
C15H20N4O
Mol. Mass.:
272.3455
SMILES:
CC(C)COc1ccc(Cc2cnc(N)nc2N)cc1
Structure:
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