Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44543
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44543
Synonyms:
2-(4-methoxyphenyl)-1-(4-methylphenyl)-2H-1,3,5-triazine-4,6-diamine;hydrochloride | 6-(4-methoxyphenyl)-1-(4-methylphenyl)-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride | MLS000532797 | SMR000140235 | [6-amino-2-(4-methoxyphenyl)-1-(p-tolyl)-2H-s-triazin-4-yl]amine;hydrochloride | cid_2851142
Type:
Small organic molecule
Emp. Form.:
C17H19N5O
Mol. Mass.:
309.3657
SMILES:
COc1ccc(cc1)C1N=C(N)N=C(N)N1c1ccc(C)cc1 |t:10,13|
Structure:
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