Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44553
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44553
Synonyms:
3-[(E)-2-(4-methoxyphenyl)ethenyl]-2-methyl-5-(4-methylphenyl)-1,2-oxazol-2-ium;tetrafluoroborate | 3-[(E)-2-(4-methoxyphenyl)ethenyl]-2-methyl-5-(4-methylphenyl)isoxazol-2-ium;tetrafluoroborate | 3-[(E)-2-(4-methoxyphenyl)vinyl]-2-methyl-5-(p-tolyl)isoxazol-2-ium;tetrafluoroborate | 3-[2-(4-methoxyphenyl)vinyl]-2-methyl-5-(4-methylphenyl)isoxazol-2-ium | MLS000324950 | SMR000160463 | cid_10363146
Type:
Small organic molecule
Emp. Form.:
C20H20NO2
Mol. Mass.:
306.3778
SMILES:
COc1ccc(\C=C\c2cc(o[n+]2C)-c2ccc(C)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: