Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM41076
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM41076
Synonyms:
4-Methyl-benzoic acid N'-[2-(6-fluoro-9H-1,3,4,9-tetraaza-fluoren-2-ylsulfanyl)-acetyl]-hydrazide | MLS000552289 | N'-[2-[(8-fluoranyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]ethanoyl]-4-methyl-benzohydrazide | N'-[2-[(8-fluoro-5H-[1,2,4]triazin[5,6-b]indol-3-yl)thio]acetyl]-4-methyl-benzohydrazide | N'-[2-[(8-fluoro-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]acetyl]-4-methylbenzohydrazide | N'-[2-[(8-fluoro-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]-1-oxoethyl]-4-methylbenzohydrazide | SMR000172467 | cid_5770206
Type:
Small organic molecule
Emp. Form.:
C19H15FN6O2S
Mol. Mass.:
410.425
SMILES:
Cc1ccc(cc1)C(=O)NNC(=O)CSc1nnc2c(n1)[nH]c1ccc(F)cc21
Structure:
Search PDB for entries with ligand similarity: