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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41659
Substrate
n/a
Meas. Tech.
Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA
EC50
>50000±n/a nM
Citation
 PubChem, PC Counter screen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41659
Synonyms:
2-(N-(3,5-dimethylisoxazol-4-yl)sulfonyl-3,5-dimethyl-anilino)-N-m-anisyl-acetamide | 2-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl-(3,5-dimethylphenyl)amino]-N-[(3-methoxyphenyl)methyl]ethanamide | 2-[N-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]-3,5-dimethylanilino]-N-[(3-methoxyphenyl)methyl]acetamide | 2-[N-[(3,5-dimethyl-4-isoxazolyl)sulfonyl]-3,5-dimethylanilino]-N-[(3-methoxyphenyl)methyl]acetamide | MLS000117417 | SMR000094367 | cid_5308908
Type:
Small organic molecule
Emp. Form.:
C23H27N3O5S
Mol. Mass.:
457.543
SMILES:
COc1cccc(CNC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)c2c(C)noc2C)c1
Structure:
Search PDB for entries with ligand similarity: