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Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM36851
Substrate
n/a
Meas. Tech.
Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA
IC50
1802±n/a nM
Citation
 PubChem, PC Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA PubChem Bioassay (2008)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM36851
Synonyms:
MLS000072751 | N-(5-Benzotriazol-1-ylmethyl-[1,3,4]thiadiazol-2-yl)-4-tert-butyl-N-ethyl-benzamide | N-[5-(1-benzotriazolylmethyl)-1,3,4-thiadiazol-2-yl]-4-tert-butyl-N-ethylbenzamide | N-[5-(benzotriazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-4-tert-butyl-N-ethyl-benzamide | N-[5-(benzotriazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-4-tert-butyl-N-ethylbenzamide | SMR000004710 | cid_649706
Type:
Small organic molecule
Emp. Form.:
C22H24N6OS
Mol. Mass.:
420.531
SMILES:
CCN(C(=O)c1ccc(cc1)C(C)(C)C)c1nnc(Cn2nnc3ccccc23)s1
Structure:
Search PDB for entries with ligand similarity: