Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM39773
Substrate
n/a
Meas. Tech.
Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA
IC50
686±n/a nM
Citation
 PubChem, PC Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA PubChem Bioassay (2008)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM39773
Synonyms:
(2Z)-3-ethyl-2-[(1-ethyl-8-methyl-2-quinolin-1-iumyl)methylidene]-1,3-benzothiazole;iodide | (2Z)-3-ethyl-2-[(1-ethyl-8-methyl-quinolin-1-ium-2-yl)methylene]-1,3-benzothiazole;iodide | (2Z)-3-ethyl-2-[(1-ethyl-8-methyl-quinolin-1-ium-2-yl)methylidene]-1,3-benzothiazole;iodide | (2Z)-3-ethyl-2-[(1-ethyl-8-methylquinolin-1-ium-2-yl)methylidene]-1,3-benzothiazole;iodide | 1-Ethyl-2-(3-ethyl-3H-benzothiazol-2-ylidenemethyl)-8-methyl-quinolinium | MLS000556089 | SMR000177972 | cid_11958727
Type:
Small organic molecule
Emp. Form.:
C22H23N2S
Mol. Mass.:
347.496
SMILES:
CCN1\C(Sc2ccccc12)=C\c1ccc2cccc(C)c2[n+]1CC
Structure:
Search PDB for entries with ligand similarity: