Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 2
Ligand
BDBM41708
Substrate
n/a
Meas. Tech.
Counterscreen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA: S1P2 Purchased Analogues
EC50
>44000±n/a nM
Citation
 PubChem, PC Counterscreen for S1P2 Agonists: Dose Response High Throughput Cell-Based Screen to Identify Activators of CRE-BLA: S1P2 Purchased Analogues PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 2
Synonyms:
EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38883.16
Organism:
Homo sapiens (Human)
Description:
Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay.
Residue:
353
Sequence:
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
  
Inhibitor
Name:
BDBM41708
Synonyms:
1-(1-benzyl-2,5-dimethyl-pyrrol-3-yl)-2-[(5-cyclopropyl-4-methyl-1,2,4-triazol-3-yl)thio]ethanone | 1-(1-benzyl-2,5-dimethylpyrrol-3-yl)-2-[(5-cyclopropyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanone | 2-[(5-cyclopropyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-1-[2,5-dimethyl-1-(phenylmethyl)pyrrol-3-yl]ethanone | 2-[(5-cyclopropyl-4-methyl-1,2,4-triazol-3-yl)thio]-1-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]ethanone | SR-01000759098-1 | cid_9268705
Type:
Small organic molecule
Emp. Form.:
C21H24N4OS
Mol. Mass.:
380.506
SMILES:
Cc1cc(C(=O)CSc2nnc(C3CC3)n2C)c(C)n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: