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Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM46001
Substrate
n/a
Meas. Tech.
SAR analysis of an In Vitro TNAP Dose Response Luminescent Assay
IC50
270±n/a nM
Citation
 PubChem, PC SAR analysis of an In Vitro TNAP Dose Response Luminescent Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM46001
Synonyms:
3-(2,4-dichloro-5-fluoro-phenyl)-N-isobutyl-1H-pyrazole-5-carboxamide | 3-(2,4-dichloro-5-fluorophenyl)-N-(2-methylpropyl)-1H-pyrazole-5-carboxamide | 3-[2,4-bis(chloranyl)-5-fluoranyl-phenyl]-N-(2-methylpropyl)-1H-pyrazole-5-carboxamide | MLS-0146309.0001 | cid_24178182
Type:
Small organic molecule
Emp. Form.:
C14H14Cl2FN3O
Mol. Mass.:
330.185
SMILES:
CC(C)CNC(=O)c1cc(n[nH]1)-c1cc(F)c(Cl)cc1Cl
Structure:
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