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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM46158
Substrate
n/a
Meas. Tech.
Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP
IC50
>100000±n/a nM
Citation
 PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM46158
Synonyms:
(2S)-2-(3,5-diethyl-2,4,6-triketo-1,3,5-triazinan-1-yl)-3-phenyl-propionic acid | (2S)-2-(3,5-diethyl-2,4,6-trioxo-1,3,5-triazinan-1-yl)-3-phenylpropanoic acid | (2S)-2-[3,5-diethyl-2,4,6-tris(oxidanylidene)-1,3,5-triazinan-1-yl]-3-phenyl-propanoic acid | MLS-0111654.0001 | cid_16654711
Type:
Small organic molecule
Emp. Form.:
C16H19N3O5
Mol. Mass.:
333.3392
SMILES:
CCn1c(=O)n(CC)c(=O)n([C@@H](Cc2ccccc2)C(O)=O)c1=O
Structure:
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