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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM37440
Substrate
n/a
Meas. Tech.
Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP
IC50
>100000±n/a nM
Citation
 PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM37440
Synonyms:
MLS000065807 | N-(1,2-oxazol-3-yl)-2-thiophen-2-yl-ethanamide | N-(1,2-oxazol-3-yl)-2-thiophen-2-ylacetamide | N-(3-isoxazolyl)-2-thiophen-2-ylacetamide | N-3-isoxazolyl-2-(2-thienyl)acetamide | N-isoxazol-3-yl-2-(2-thienyl)acetamide | SMR000080496 | cid_1246102
Type:
Small organic molecule
Emp. Form.:
C9H8N2O2S
Mol. Mass.:
208.237
SMILES:
O=C(Cc1cccs1)Nc1ccon1
Structure:
Search PDB for entries with ligand similarity: