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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM31704
Substrate
n/a
Meas. Tech.
Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP
IC50
3655±n/a nM
Citation
 PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM31704
Synonyms:
MLS000050353 | N-(2,3-di-2-furyl-6-quinoxalinyl)-1-azepanecarboxamide | N-[2,3-bis(2-furanyl)-6-quinoxalinyl]-1-azepanecarboxamide | N-[2,3-bis(2-furyl)quinoxalin-6-yl]azepane-1-carboxamide | N-[2,3-bis(furan-2-yl)quinoxalin-6-yl]azepane-1-carboxamide | SMR000077614 | cid_2214811
Type:
Small organic molecule
Emp. Form.:
C23H22N4O3
Mol. Mass.:
402.4458
SMILES:
O=C(Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1)N1CCCCCC1
Structure:
Search PDB for entries with ligand similarity: