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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM46264
Substrate
n/a
Meas. Tech.
Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP
IC50
84779±n/a nM
Citation
 PubChem, PC Fluorescent secondary assay for dose-response confirmation of chemical inhibitors of HePTP PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM46264
Synonyms:
3-[2-azaspiro[5.5]undecan-2-yl-(1-cyclopentyl-1,2,3,4-tetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one | 3-[2-azaspiro[5.5]undecan-2-yl-(1-cyclopentyl-5-tetrazolyl)methyl]-6-methyl-1H-quinolin-2-one | 3-[2-azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-one | 3-[2-azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-carbostyril | MLS-0412204.0001 | cid_3182456
Type:
Small organic molecule
Emp. Form.:
C27H36N6O
Mol. Mass.:
460.6143
SMILES:
Cc1ccc2[nH]c(=O)c(cc2c1)C(N1CCCC2(CCCCC2)C1)c1nnnn1C1CCCC1
Structure:
Search PDB for entries with ligand similarity: