Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM46289
Substrate
n/a
Meas. Tech.
Estrogen Receptor (beta) binding: Dose Response of Primary Screen Assay
EC50
438.4±n/a nM
Citation
 PubChem, PC Estrogen Receptor (beta) binding: Dose Response of Primary Screen Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM46289
Synonyms:
2-methyl-7-oxidanyl-3-phenoxy-chromen-4-one | 7-hydroxy-2-methyl-3-phenoxy-1-benzopyran-4-one | 7-hydroxy-2-methyl-3-phenoxy-chromone | 7-hydroxy-2-methyl-3-phenoxychromen-4-one | MLS000104599 | SMR000054532 | cid_5310638
Type:
Small organic molecule
Emp. Form.:
C16H12O4
Mol. Mass.:
268.2641
SMILES:
Cc1oc2cc(O)ccc2c(=O)c1Oc1ccccc1
Structure:
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