Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM46297
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
EC50
42840±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) PubChem Bioassay (2008)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM46297
Synonyms:
2-[(1,1-diketo-1,2-benzothiazol-3-yl)-(4-pyridylmethyleneamino)amino]ethanol;hydrochloride | 2-[(1,1-dioxo-1,2-benzothiazol-3-yl)-(pyridin-4-ylmethylideneamino)amino]ethanol;hydrochloride | 2-[[1,1-bis(oxidanylidene)-1,2-benzothiazol-3-yl]-(pyridin-4-ylmethylideneamino)amino]ethanol;hydrochloride | MLS000682942 | SMR000313025 | cid_16193778 | isonicotinaldehyde (1,1-dioxido-1,2-benzisothiazol-3-yl)(2-hydroxyethyl)hydrazone
Type:
Small organic molecule
Emp. Form.:
C15H14N4O3S
Mol. Mass.:
330.362
SMILES:
OCCN(N=Cc1ccncc1)C1=NS(=O)(=O)c2ccccc12 |w:4.3,t:13|
Structure:
Search PDB for entries with ligand similarity: