Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM32280
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
33670±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM32280
Synonyms:
MLS000534769 | N-(4-acetylphenyl)-2,3-bis(2-furanyl)-6-quinoxalinecarboxamide | N-(4-acetylphenyl)-2,3-bis(2-furyl)quinoxaline-6-carboxamide | N-(4-acetylphenyl)-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | N-(4-acetylphenyl)-2,3-di-2-furyl-6-quinoxalinecarboxamide | N-(4-ethanoylphenyl)-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | SMR000142225 | cid_1331726
Type:
Small organic molecule
Emp. Form.:
C25H17N3O4
Mol. Mass.:
423.4202
SMILES:
CC(=O)c1ccc(NC(=O)c2ccc3nc(-c4ccco4)c(nc3c2)-c2ccco2)cc1
Structure:
Search PDB for entries with ligand similarity: