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Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM33089
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
2130±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM33089
Synonyms:
(3-methyl-4-pyrrolidino-phenyl)amine;hydrochloride | 3-methyl-4-(1-pyrrolidinyl)aniline;hydrochloride | 3-methyl-4-pyrrolidin-1-yl-aniline;hydrochloride | 3-methyl-4-pyrrolidin-1-ylaniline;hydrochloride | MLS000566003 | SMR000153134 | cid_109673
Type:
Small organic molecule
Emp. Form.:
C11H16N2
Mol. Mass.:
176.2581
SMILES:
Cc1cc(N)ccc1N1CCCC1
Structure:
Search PDB for entries with ligand similarity: