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Target
Bcl-2-like protein 10 [11-204]
Ligand
BDBM32316
Substrate
n/a
Meas. Tech.
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein.
EC50
1320±n/a nM
Citation
 PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 10 [11-204]
Synonyms:
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21981.77
Organism:
Homo sapiens (Human)
Description:
gi_23396469
Residue:
194
Sequence:
MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
  
Inhibitor
Name:
BDBM32316
Synonyms:
MLS000704595 | SMR000231990 | cid_5774988 | ethyl 6-chloro-2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H12ClNO4
Mol. Mass.:
353.756
SMILES:
CCOC(=O)c1c2-c3ccccc3C(=O)c3c(Cl)ccc([nH]c1=O)c23
Structure:
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