Reaction Details Report a problem with these data
Target
Bcl-2-like protein 2
Ligand
BDBM46311
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
44220±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM46311
Synonyms:
1,3-benzodioxol-5-yl(2,4-dimethylbenzyl)amine | 1,3-benzodioxol-5-yl-(2,4-dimethylbenzyl)amine | MLS000059228 | N-[(2,4-dimethylphenyl)methyl]-1,3-benzodioxol-5-amine | SMR000069692 | cid_784440
Type:
Small organic molecule
Emp. Form.:
C16H17NO2
Mol. Mass.:
255.3117
SMILES:
Cc1ccc(CNc2ccc3OCOc3c2)c(C)c1
Structure:
Search PDB for entries with ligand similarity: