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Target
Bcl-2-like protein 2
Ligand
BDBM31713
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
16370±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM31713
Synonyms:
1-Cyclopropyl-3-(2,3-di-furan-2-yl-quinoxalin-6-yl)-urea | 1-[2,3-bis(2-furanyl)-6-quinoxalinyl]-3-cyclopropylurea | 1-[2,3-bis(2-furyl)quinoxalin-6-yl]-3-cyclopropyl-urea | 1-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-cyclopropyl-urea | 1-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-cyclopropylurea | MLS000121102 | SMR000118524 | cid_1072898
Type:
Small organic molecule
Emp. Form.:
C20H16N4O3
Mol. Mass.:
360.366
SMILES:
O=C(NC1CC1)Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: