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Target
Bcl-2-like protein 2
Ligand
BDBM32277
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
2430±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM32277
Synonyms:
(m-anisylideneamino)-([1,2,4]triazolo[3,4-a]phthalazin-6-yl)amine | MLS000555524 | N-[(3-methoxyphenyl)methylideneamino]-[1,2,4]triazolo[3,4-a]phthalazin-6-amine | N-[1-(3-Methoxy-phenyl)-meth-(E)-ylidene]-N'-[1,2,4]triazolo[3,4-a]phthalazin-6-yl-hydrazine | SMR000147241 | cid_1384684
Type:
Small organic molecule
Emp. Form.:
C17H14N6O
Mol. Mass.:
318.3327
SMILES:
COc1cccc(CN=Nc2nn3cnnc3c3ccccc23)c1 |w:9.9|
Structure:
Search PDB for entries with ligand similarity: