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Target
Bcl-2-like protein 2
Ligand
BDBM32298
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
3560±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM32298
Synonyms:
(E)-1-phenyl-3-[5-(p-tolyl)-2-furyl]prop-2-en-1-one | (E)-3-[5-(4-methylphenyl)-2-furanyl]-1-phenyl-2-propen-1-one | (E)-3-[5-(4-methylphenyl)furan-2-yl]-1-phenyl-prop-2-en-1-one | (E)-3-[5-(4-methylphenyl)furan-2-yl]-1-phenylprop-2-en-1-one | 1-Phenyl-3-(5-p-tolyl-furan-2-yl)-propenone | MLS000567588 | SMR000175496 | cid_5706152
Type:
Small organic molecule
Emp. Form.:
C20H16O2
Mol. Mass.:
288.3398
SMILES:
Cc1ccc(cc1)-c1ccc(\C=C\C(=O)c2ccccc2)o1
Structure:
Search PDB for entries with ligand similarity: