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Target
Bcl-2-like protein 2
Ligand
BDBM32308
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
10550±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM32308
Synonyms:
(Z)-1-phenyl-3-(5-phenyl-2-furanyl)-2-propen-1-one | (Z)-1-phenyl-3-(5-phenyl-2-furyl)prop-2-en-1-one | (Z)-1-phenyl-3-(5-phenylfuran-2-yl)prop-2-en-1-one | MLS000722313 | SMR000236018 | cid_5708162
Type:
Small organic molecule
Emp. Form.:
C19H14O2
Mol. Mass.:
274.3133
SMILES:
O=C(\C=C/c1ccc(o1)-c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: