Reaction Details Report a problem with these data
Target
Bcl-2-like protein 2
Ligand
BDBM33192
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
4030±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33192
Synonyms:
3,4,5-trihydroxy-N'-[(1Z)-1-(4-nitrophenyl)ethylidene]benzohydrazide | 3,4,5-trihydroxy-N-[(Z)-1-(4-nitrophenyl)ethylideneamino]benzamide | 3,4,5-trihydroxy-N-[1-(4-nitrophenyl)ethylideneamino]benzamide | MLS000685625 | N-[1-(4-nitrophenyl)ethylideneamino]-3,4,5-tris(oxidanyl)benzamide | SMR000312589 | cid_4099654
Type:
Small organic molecule
Emp. Form.:
C15H13N3O6
Mol. Mass.:
331.2802
SMILES:
CC(=NNC(=O)c1cc(O)c(O)c(O)c1)c1ccc(cc1)[N+]([O-])=O |w:2.2|
Structure:
Search PDB for entries with ligand similarity: