Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM42583
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
7419±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM42583
Synonyms:
1-Hydroxy-7,8,9,10-tetrahydro-6H-12-thia-5a,11-diaza-cyclohepta[b]fluoren-5-one | MLS000074023 | SMR000009844 | cid_534281
Type:
Small organic molecule
Emp. Form.:
C15H14N2O2S
Mol. Mass.:
286.349
SMILES:
Oc1cccc2c1sc1nc3CCCCCn3c(=O)c21
Structure:
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