Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM40249
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
5056±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM40249
Synonyms:
5-(1,3-benzothiazol-2-yl)-N-propyl-2-thiophenecarboxamide | 5-(1,3-benzothiazol-2-yl)-N-propyl-thiophene-2-carboxamide | 5-(1,3-benzothiazol-2-yl)-N-propylthiophene-2-carboxamide | MLS000566279 | SMR000153391 | cid_2452036
Type:
Small organic molecule
Emp. Form.:
C15H14N2OS2
Mol. Mass.:
302.414
SMILES:
CCCNC(=O)c1ccc(s1)-c1nc2ccccc2s1
Structure:
Search PDB for entries with ligand similarity: