Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46376
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
7657±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46376
Synonyms:
2-(2-naphthalenylthio)-N-pyridin-4-ylacetamide | 2-(2-naphthylthio)-N-(4-pyridyl)acetamide | 2-naphthalen-2-ylsulfanyl-N-pyridin-4-yl-ethanamide | 2-naphthalen-2-ylsulfanyl-N-pyridin-4-ylacetamide | MLS000564987 | SMR000152174 | cid_2368480
Type:
Small organic molecule
Emp. Form.:
C17H14N2OS
Mol. Mass.:
294.371
SMILES:
O=C(CSc1ccc2ccccc2c1)Nc1ccncc1
Structure:
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