Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM46413
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 inhibition
IC50
4050±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM46413
Synonyms:
2-benzyl-5-(4-bromophenyl)pyrazol-3-amine | 5-(4-bromophenyl)-2-(phenylmethyl)-3-pyrazolamine | 5-(4-bromophenyl)-2-(phenylmethyl)pyrazol-3-amine | MLS000712366 | SMR000282133 | [2-benzyl-5-(4-bromophenyl)pyrazol-3-yl]amine | cid_693933
Type:
Small organic molecule
Emp. Form.:
C16H14BrN3
Mol. Mass.:
328.206
SMILES:
Nc1cc(nn1Cc1ccccc1)-c1ccc(Br)cc1
Structure:
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